Randomized controlled trial finds intermittent pneumatic compression reduces intradialytic hypotension and improves hemodynamic indicators in patients undergoing maintenance hemodialysis.
Background Patients undergoing maintenance hemodialysis (MHD) suffer from intradialytic hypotension (IDH), leading to a higher risk of mortality and hospitalization. Intermittent pneumatic compression (IPC) may be a potential intervention to prevent the decline of blood pressure during hemodialysis. However, evidence about the effects of IPC on intradialytic hemodynamic changes in patients undergoing MHD is lacking. This study aimed to evaluate the effects of IPC on intradialytic hemodynamic changes in patients undergoing MHD. Methods In this randomized clinical trial, 30 patients undergoing MHD were randomly assigned to the IPC group (n = 14) and the control group (n = 16). Participants in the control group received usual care and patients in the IPC group received IPC during all dialysis sessions for 12 weeks. The effects of IPC on hemodynamic indicators were analyzed by using a generalized estimating equation model. Results A total of 26 participants completed the study. The adherence of IPC was 94.2%. The changes in hemodynamic indicators (i.e., blood pressure and heart rate) from pre-dialysis were significantly slighter in the IPC group than in the control group at all time points during dialysis (P < 0.05). IDH incidences also occurred less frequently in the IPC group than in the control group (P < 0.01). Conclusion Intradialytic IPC promotes hemodynamic indicators and reduces IDH occurrence in patients undergoing MHD. The compliance and safety of intradialytic IPC were satisfactory. Intradialytic IPC could be implemented in clinical settings to maintain hemodynamic stability during hemodialysis.
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Liu et al. (2025) studied this question.
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