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October 16, 2025Annals of HematologyOpen Access

Results from a US modified Delphi consensus to define disease progression and disease modification in polycythemia Vera

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Authors

PBPrithviraj BoseENEmily NaglerMNMuhammad Sarfraz Nawaz

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Overview

Modified Delphi consensus identified key factors affecting disease progression and treatment in polycythemia vera, suggesting improved patient outcomes.

Key Points

  • A consensus of 39 out of 41 statements achieved agreement, highlighting the importance of defining disease progression in polycythemia vera.
  • Key factors influencing progression to myelofibrosis and leukemia include advanced age and specific mutations.
  • A modified-Delphi method utilized a panel of specialists to develop and evaluate consensus statements on disease management and treatment.
  • Recommendations aim to enhance understanding of polycythemia vera disease course, potentially leading to more effective therapeutic strategies.

Cite This Study

Bose et al. (2025) studied this question.

synapsesocial.com/papers/68f147cc724575985c3fd274https://doi.org/10.1007/s00277-025-06641-2
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