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This is a Experimental Study study.

The Loading of Dipyridamole and Calcium Sulfate into the Gelatin-Coated Porous Bioceramics to Synergistically Regulate Segmental Bone Regeneration

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The developed scaffolds bridged ulnar bone defects in rabbits within 12 weeks, demonstrating effective bone regeneration.
In vitro studies confirmed that gelatin, dipyridamole, calcium sulfate, and TCP improved mesenchymal stem cell behaviors related to bone formation.
In vivo experiments revealed that the scaffolds could capture endogenous MSCs, facilitating a desirable degradation rate during healing.
The synergistic effect of the four components regulated the osteoblastic-osteoclastic imbalance in bone remodeling, enhancing overall scaffolding efficacy.

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Experimental approach shows enhanced bone healing in rabbits with calcium sulfate and dipyridamole, indicating promising scaffold strategies.

Wu et al. (2025) studied this question.

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Experimental approach shows enhanced bone healing in rabbits with calcium sulfate and dipyridamole, indicating promising scaffold strategies.