Simulation of Propofol Target-Controlled Infusion up to Time of Delivery in Cesarean Section: A Bench Study

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Discussion

Simulation study reveals anesthetic dose and delivery timing in cesarean deliveries, highlighting infusion pauses.

Estimates show that 40% to 50% of cesarean deliveries occurred during infusion pauses, indicating timing challenges.
Among 50 women, the average propofol dose was 19 mg at 6 mcg/mL and 13 mg at 8 mcg/mL during cesarean sections.
Propofol administration was standardized through a target-controlled infusion, indicating potential safety in anesthetic management.
Emergency circumstances predicted delivery during pauses, emphasizing the need for tailored dosing and monitoring.

Osthoff et al. (2025) studied this question.

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