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This is a Quantitative Study study (also classified as: Experimental Study).

Sustainable Vesicular Nanosystems Incorporated Into Film-Forming Gels for Niacinamide Cutaneous Delivery

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Nanocarriers containing niacinamide significantly improved skin permeation compared to the free active ingredient.
Physicochemical characterization revealed the nanocarriers' stability and effectiveness over 30 days at room temperature.
The film-forming gel system exhibited suitable rheological and bioadhesion properties for topical use.
Antioxidant activity significantly increased in phytantriol-based nanocarriers assessed by DPPH and β-carotene methods.

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This investigation demonstrates enhanced skin permeation of niacinamide in a film-forming gel, suggesting better topical application outcomes.

Fraga et al. (2025) studied this question.

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This investigation demonstrates enhanced skin permeation of niacinamide in a film-forming gel, suggesting better topical application outcomes.