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Case Report: E2 luteal phase priming in a stop GnRH agonist combined with GnRH antagonist using a delta follitropin protocol in a poor responder: clinical case

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This case illustrates that combining luteal estradiol priming with a stop GnRH agonist enhances IVF outcomes.
The patient produced eight mature oocytes, leading to the development of two usable blasts, underscoring this method's effectiveness.
The novel protocol includes E2 priming, GnRH agonist suppression, and delta follitropin, indicating a potential advancement in treatment strategies.
The findings highlight the need for larger-scale studies to validate this combined stimulation protocol for poor responders.

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Case report shows dual suppression of FSH and LH with combined E2 and GnRH protocols in infertility treatment.

Berrocal et al. (2025) studied this question.

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