October 17, 2025Frontiers in EndocrinologyOpen Access

Comparison between 75-g and 100-g oral glucose tolerance tests using international association of diabetes and pregnancy study group one-step diagnostic threshold to detect gestational diabetes mellitus

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Authors

LZLili ZhouTongji University DLDong LiuTangshan People's Hospital HSHongqing SongAviation Industry Corporation of China (China)

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Implication

Retrospective study finds no significant differences in GDM detection rates between 75g and 100g OGTT, suggesting a need for standardized diagnostic criteria.

Key Points

No significant differences in GDM detection rates were found between the 75g and 100g OGTT groups.
The 100g OGTT group had higher 1h and 2h blood glucose levels compared to the 75g group, with p < 0.01.
Both OGTT groups exhibited similar trends in adverse outcomes risks, with no significant differences observed.
Standardizing screening strategies for GDM is warranted to improve clinical consistency, as per the IADPSG criteria.

Cite This Study

Zhou et al. (2025) studied this question.

synapsesocial.com/papers/68f199ccde32064e504dd0ab https://doi.org/10.3389/fendo.2025.1512499

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Implication

Retrospective study finds no significant differences in GDM detection rates between 75g and 100g OGTT, suggesting a need for standardized diagnostic criteria.

Comparison between 75-g and 100-g oral glucose tolerance tests using international association of diabetes and pregnancy study group one-step diagnostic threshold to detect gestational diabetes mellitus

Discussion

Member takes

Implication

Key Points

Cite This Study

Comparison between 75-g and 100-g oral glucose tolerance tests using international association of diabetes and pregnancy study group one-step diagnostic threshold to detect gestational diabetes mellitus

Discussion

Member takes

Implication

Key Points

Cite This Study

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