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Observational analysis indicates a lack of correlation between urinary cotinine and lung function among tobacco workers, suggesting potential health risks.
This study investigated the association between urinary cotinine levels and lung function among tobacco workers in Jember Regency, a major tobacco-producing region in Indonesia. A total of 48 respondents were included based on specific inclusion and exclusion criteria. Urinary cotinine levels were measured using enzyme-linked immunosorbent assay (ELISA), and lung function was assessed via spirometry. Based on FEV1/FVC ratios, 58% of participants exhibited restrictive lung patterns, 29% showed obstructive patterns, and 13% had normal pulmonary function. Statistical analysis conducted using SPSS, with a significance level set at p < 0.05, indicated no statistically significant correlation between urinary cotinine levels and lung function.
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Nofica et al. (2025) studied this question.
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