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The Effectiveness Of Intra-Articular Hyaluronic Acid Injection Combined With Oral Nonsteroidal Anti-Inflammatory Drugs In The Treatment Of Knee Osteoarthritis

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This study demonstrates improved clinical efficacy and reduced pain in KOA patients using HA with NSAIDs.

The combined treatment improved clinical outcomes in knee osteoarthritis patients significantly.
After treatment, the KOOS score was significantly higher in the study group compared to the control group.
Pain levels measured by VAS score decreased significantly in the study group, confirming its effectiveness.
No significant increase in adverse reactions was observed in either group, suggesting safety in treatment.

A 2025 study studied this question.

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View Full Paper

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This study demonstrates improved clinical efficacy and reduced pain in KOA patients using HA with NSAIDs.

The combined treatment improved clinical outcomes in knee osteoarthritis patients significantly.
After treatment, the KOOS score was significantly higher in the study group compared to the control group.
Pain levels measured by VAS score decreased significantly in the study group, confirming its effectiveness.
No significant increase in adverse reactions was observed in either group, suggesting safety in treatment.

A 2025 study studied this question.

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