Analysis of DNA-targeting using chimeric probes and oligonucleotides, highlighting their specificity and efficiency.
DNA-targeting properties of heteroduplexes between intercalator-functionalized oligonucleotides and various Xeno RNAs (i.e., LNA/MOE mixmers, or fully modified MOE, O2'-Me, or 2'-F strands) are disclosed. Chimeric Invader:LNA/MOE probes and some single-stranded...
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Everly et al. (2025) studied this question.
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