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Observational analysis shows propranolol reduces rapid postnatal growth in atypical congenital hemangioma, suggesting a valuable treatment option.
Congenital hemangiomas are traditionally regarded to be fully grown by birth and are classified into three main subtypes based on their postnatal behavior, namely rapidly involuting congenital hemangioma, noninvoluting congenital hemangioma, and partially involuting congenital hemangioma. However, studies have reported atypical behavior, such as large postnatal expansion, in some congenital hemangiomas. Although there is no consensus on the medical options for treating congenital hemangiomas, propranolol has been successfully reported in several cases of large congenital hemangiomas to ameliorate complications, such as mass effect. Herein, we present one such atypical case of a giant congenital hemangioma with accelerated postnatal growth, responding to treatment with propranolol, highlighting the potential of this therapeutic option.
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Ong et al. (2025) studied this question.
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