Analysis reveals changes in stereochemistry with borohydride reduction of tert-butyl-cyclohexanone in water, suggesting complex interactions.
Part one of this topic was posted more than ten years ago. I clearly forgot about it, so belatedly, here is part 2 – dealing with the stereochemistry of the reduction of tert-butyl-cyclohexanone by borohydride in water.
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Henry S. Rzepa (2025) studied this question.
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