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October 23, 2025Frontiers in EndocrinologyOpen Access

Growth hormone therapy and chromosomal mosaicism in turner syndrome: 25 years of growth outcomes in Taiwan

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Retrospective analysis shows growth hormone therapy improves height in Turner syndrome girls, indicating early treatment is crucial.

Growth hormone therapy improves height outcomes in turner syndrome patients with varying karyotypes.
Mean growth velocity improved during treatment, highlighting the effectiveness of therapy in short stature.
Multivariable linear regression identified bone age and initial height as key predictors of final height.
Karyotype did not significantly impact adult height, emphasizing individualized treatment for better outcomes.

Chang et al. (2025) studied this question.

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