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October 23, 2025Open Access

Exosomal MicroRNAs in Cancer: Mechanisms, Clinical Applications, and Challenges in Biomarker Discovery

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Authors

AMAshutosh Kumar MauryaAMAshish Kumar MauryaJMJordi Muntané

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Overview

Review highlights exosomal microRNAs aiding early cancer detection and therapeutic monitoring, pointing to challenges in standardization and clinical validation.

Key Points

  • Exosomal microRNAs improve early cancer detection and prognosis, with significant implications for therapeutic monitoring.
  • Biomarker discovery based on liquid biopsies has identified key roles of miRNAs in cancer progression and metastasis.
  • Technological advancements in exosome isolation and profiling are essential to harness the potential of exosomal miRNAs.
  • Standardization and variability in miRNA expression across cancer types remain challenges for their clinical application.

Cite This Study

Maurya et al. (2025) studied this question.

synapsesocial.com/papers/68f9bad6d7353cfcfc68f2f2https://doi.org/10.20944/preprints202510.0905.v2
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Exosomal MicroRNAs in Cancer: Mechanisms, Clinical Applications, and Challenges in Biomarker Discovery2025
  2. 2Exosomal microRNAs in breast cancer: towards theranostic applications2024 · 7 citations
  3. 3Exosomes in Cancer Biology: Emerging Biomarkers and Therapeutic Targets2026
  4. 4Exosomal MicroRNA: Diagnostic Potential and Role in Breast Cancer Dissemination2025
  5. 5Exosomal microRNAs in colorectal cancer communication networks: implications for metastasis, therapy resistance, and precision medicine2026 · 1 citations