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October 23, 2025Reproductive Medicine and BiologyOpen Access

Investigating the Link Between Intimate Health, Hygiene and Sexual Practices and the Vaginal Microbiome—The INTIMATE Study

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Authors

KMKristina MagoutasAHAlexandra M. HoldcroftMWMelanie Walls

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Overview

Observational analysis demonstrated monogamous women show significant vaginal microbiome differences, indicating hygiene practices affect infections.

Key Points

  • Infections were fewer with regular perineal washing, while recurrent thrush linked to internal washing.
  • Monogamous women had lower L. crispatus and higher L. iners levels, compared to those with multiple partners.
  • Analysis involved vaginal microbiome examination via 16S rRNA gene sequencing in 96 non-pregnant women.
  • Microbial composition varied with menstrual status, highlighting the importance of intimate health practices.

Cite This Study

Magoutas et al. (2025) studied this question.

synapsesocial.com/papers/68f9d6583f378872224924a3https://doi.org/10.1002/rmb2.12685
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Differences in the composition of vaginal microbial communities found in healthy Caucasian and black women2007 · 582 citations
  2. 2Bacteria in the Vaginal Microbiome Alter the Innate Immune Response and Barrier Properties of the Human Vaginal Epithelia in a Species-Specific Manner2014 · 312 citations
  3. 3The Female Vaginal Microbiome in Health and Bacterial Vaginosis2021 · 470 citations
  4. 4Vaginal health and hygiene practices and product use in Canada: a national cross-sectional survey2018 · 89 citations
  5. 5Male-Partner Treatment to Prevent Recurrence of Bacterial Vaginosis2025 · 94 citations