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October 23, 2025Frontiers in OncologyOpen Access

Long noncoding RNAs involved in therapeutic response: implications for cervical cancer drug resistance

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Authors

STSamuel Trujano-CamachoCCCarlos Contreras-RomeroVGVerónica García-Castillo

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Overview

Analysis reveals long noncoding RNAs influence drug resistance in cervical cancer, suggesting new therapeutic targets.

Key Points

  • Drug resistance is significantly mediated by long noncoding RNAs in cervical cancer, with key implications for treatment strategies.
  • Resistance mechanisms involve drug efflux, DNA repair, and evasion of cell death, posing challenges for therapeutic efficacy.
  • This literature review discusses resistance mechanisms and identifies lncRNAs as potential therapeutic targets for cervical cancer.
  • Highlighting the role of lncRNAs may enable the development of response markers and improve treatment outcomes in cervical cancer.

Cite This Study

Trujano-Camacho et al. (2025) studied this question.

synapsesocial.com/papers/68fa1210f9f8b44535bfcc3bhttps://doi.org/10.3389/fonc.2025.1644104
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Also Consider

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  1. 1Unveiling the mechanisms and challenges of cancer drug resistance2024 · 400 citations
  2. 2Overcoming drug efflux-based multidrug resistance in cancer with nanotechnology2012 · 190 citations
  3. 3Key Molecular Events in Cervical Cancer Development2019 · 266 citations
  4. 4LncRNA NEAT1 regulation of the miR-101-3p/RAC1 axis affects cervical cancer aerobic glycolysis and progression2025 · 8 citations