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This is a Systematic Review study.

October 31, 2025DiagnosticsOpen Access

Systematic Review of Line-Field Confocal Optical Coherence Tomography for Diagnosing Pre-Malignant and Malignant Keratinocytic Lesions: Optimising the Workflow

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Line-field confocal optical coherence tomography reliably identifies actinic keratosis, Bowen’s disease, and squamous cell carcinoma.
Digital imaging optimisations yielded improved image resolution and interobserver concordance.
Analysis of eleven studies highlights LC-OCT visualisation of key histopathological correlates such as hyperkeratosis and acanthosis.
Establishing standardised imaging protocols could enhance diagnostic accuracy and support artificial intelligence integration.

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Implication

Systematic review demonstrates reliable detection of actinic keratosis, Bowen’s disease, and squamous cell carcinoma using line-field confocal optical coherence tomography, indicating workflow optimis

Cite This Study

Marques et al. (2025) studied this question.

synapsesocial.com/papers/6903fee5b25c631a4265ff75 https://doi.org/10.3390/diagnostics15212746

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Systematic Review of Line-Field Confocal Optical Coherence Tomography for Diagnosing Pre-Malignant and Malignant Keratinocytic Lesions: Optimising the Workflow

Key Points

Discussion

Implication

Cite This Study

Systematic Review of Line-Field Confocal Optical Coherence Tomography for Diagnosing Pre-Malignant and Malignant Keratinocytic Lesions: Optimising the Workflow

Key Points

Discussion

Implication

Cite This Study

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