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November 8, 2025Open Access

Multi-omic characterization of the sow colostrum and milk microbiome and proteome

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Authors

DHDevin B. HolmanKGKatherine E. GzylAKArun Kommadath

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Overview

Combined analysis shows microbiome shifts and pathogenic species in sow milk, indicating health implications for neonates.

Key Points

  • Microbiome shifts during lactation influence neonatal health through potential host-microbe interactions.
  • Analysis identifies multiple antimicrobial resistance genes linked to pathogenic species in sow milk.
  • Proteomics reveal changes in immune and metabolic protein composition across lactation stages.
  • Metagenomic techniques enable detailed understanding of microbial diversity and functional potential in colostrum.

Cite This Study

Holman et al. (2025) studied this question.

synapsesocial.com/papers/690e8b6ca5b062d7a4e736a9https://doi.org/10.1101/2025.11.05.686862
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Bacterial profiles of the oral, vaginal, and rectal mucosa and colostrum of periparturient sows2024
  2. 2Structural and functional characteristics of faecal, vaginal and colostrum microbiota in high-yielding sows2026
  3. 3Multi-omics profiling of sow colostrum and faecal microbiota reveals parity-dependent and independent factors associated with piglet survival and growth2026
  4. 4The Colostrum Chronicles: Identifying Porcine Milk Oligosaccharides in Colostrum and Investigating Their Role in Litter Performance2026
  5. 5Identification of core microbiotas in European sows during gestation and lactation: links to performance2026