Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health

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Research reveals lipid metabolism alters cognitive decline in Alzheimer's disease, suggesting bioenergetics may influence risk factors.

Cognitive decline is significantly influenced by alterations in lipid metabolism and bioenergetics.
Key findings include the role of cholesterol and polyunsaturated fatty acids in mitochondrial function.
The investigation involved genetic studies exploring apolipoprotein E in relation to neuroinflammation.
Potential therapeutic targets highlight metabolic modulators and lifestyle strategies for Alzheimer's treatment.

Maioli et al. (2025) studied this question.

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