What question did this study set out to answer?

This study investigates the association between estimated pulse wave velocity and stroke risk in middle-aged and elderly individuals in China.

November 21, 2025PLoS ONEOpen Access

Association between estimated pulse wave velocity and stroke in middle-aged and elderly Chinese: A nationwide cohort study

View Full Paper

Ask AI

Bookmark

Authors

Cohort study shows elevated estimated pulse wave velocity raises stroke risk in middle-aged individuals, suggesting preventive strategies.

This study investigates the association between estimated pulse wave velocity and stroke risk in middle-aged and elderly individuals in China.
Cohort study with 9,190 participants from CHARLS (2011) and follow-ups in 2013, 2015, and 2018.
Participants' ePWV values were categorized into tertiles for analysis.
Stroke was defined based on the occurrence during follow-up assessments.
Cox proportional hazards regression models evaluated longitudinal associations.
Increased stroke risk was observed for higher ePWV tertiles compared to the first tertile.
The second tertile showed a 40% higher risk of stroke (HR = 1.40), while the third tertile showed a 42% higher risk (HR = 1.42).
Nonlinear dose-response relationship between ePWV and stroke risk was confirmed (P nonlinear = 0.001).

Zheng et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark

Cohort study shows elevated estimated pulse wave velocity raises stroke risk in middle-aged individuals, suggesting preventive strategies.