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November 21, 2025Frontiers in MedicineOpen Access

Reduction of surgical-site infections and improvement of scar parameters with a uniform fractional ultra-pulse CO₂ laser protocol in cosmetic surgery: a five-center retrospective cohort

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Authors

QXQinghua XuHLHaoran LiJZJu-Hui Zhao

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Overview

Multicenter analysis of laser treatment shows reduced infections and improved elasticity in cosmetic surgery patients, suggesting enhanced recovery.

Key Points

  • This study aims to assess the impact of fractional ultra-pulse CO₂ laser therapy on surgical-site infections and scar outcomes in cosmetic surgery.
  • Conducted as a multicenter retrospective cohort study involving 562 adults
  • Patients underwent various cosmetic surgeries such as rhinoplasty, liposuction, and abdominoplasty
  • 324 patients received a uniform three-stage laser protocol alongside a five-day antibiotic regimen
  • Analyses included Welch's t-test, Fisher's exact test, Kaplan-Meier curves, and Cox regression models.
  • Laser patients experienced significantly faster healing (13.8 vs. 17.0 days; p<0.001)
  • Surgical-site infections reduced from 59% to 15% (p<0.001)
  • Scars were thinner (2.44 mm vs. 3.14 mm; p<0.001) and showed improved elasticity and pigmentation
  • Quality of life and patient satisfaction scores favored the laser group, all with p<0.001

Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/6924e3ffc0ce034ddc34f6b9https://doi.org/10.3389/fmed.2025.1642041
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