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November 20, 2025Tropical Doctor

Clinical profile and predictors of biochemical markers of metabolic bone disease in very preterm neonates: An observational study

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Authors

SKShrutiprajna KarTSTanushree SahooTSTapas Som

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Overview

Observational study identifies enteral feeding delays as predictors of metabolic bone disease in preterm neonates, implicating nutritional care.

Key Points

  • This research aims to understand clinical factors and predictors of metabolic bone disease in very preterm neonates.
  • Observational study design focused on very preterm neonates
  • Assessment of biochemical markers for metabolic bone disease
  • Logistic regression analysis to identify predictors of disease associated with feeding and clinical factors
  • Metabolic bone disease defined by specific serum phosphate and alkaline phosphatase levels
  • Delayed attainment of full enteral feeding significantly predicted the development of metabolic bone disease
  • Key risk factors include lower gestational age, birth weight, cholestasis, and bronchopulmonary dysplasia

Cite This Study

Kar et al. (2025) studied this question.

synapsesocial.com/papers/6924f074c0ce034ddc34faafhttps://doi.org/10.1177/00494755251397206
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Profile of metabolic bone disease in extremely low birth weight (ELBW) and very low birth weight (VLBW) neonates2024 · 3 citations
  2. 2Biochemical metabolic bone disease in preterm infants: clinical determinants, markers and risk of fracture in a cohort study2026
  3. 3Metabolic bone disease in extremely preterm infants: incidence, risk factors, and outcomes from a structured bone health program2025 · 2 citations
  4. 4Analysis of clinical risk factors for metabolic bone disease of prematurity2024 · 5 citations
  5. 5Incidence of Metabolic Bone Disease in Preterms <32 Weeks Gestation in a Tertiary Care Center: A Prospective Observational Study2026 · 1 citations