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February 5, 2026Journal of Neonatology

Incidence of Metabolic Bone Disease in Preterms <32 Weeks Gestation in a Tertiary Care Center: A Prospective Observational Study

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Authors

APAnupama S PillaiARAswathy RahulSKSobha Kumar

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Overview

Prospective observational study estimates metabolic bone disease incidence in preterm infants, suggesting the need for timely intervention.

Key Points

  • The goal is to estimate the incidence of metabolic bone disease in preterm infants under 32 weeks gestation and examine associated clinical factors.
  • Conducted a prospective observational study in a neonatal intensive care unit.
  • Included all preterm babies born under 32 weeks gestation with parental consent.
  • Evaluated incidence of metabolic bone disease and clinical profiles.
  • The incidence of metabolic bone disease was found to be 40%.
  • 88.8% of cases were detected by 2 weeks of postnatal age, with late presentation in lower gestational ages.
  • 22.38% of babies did not respond to treatment in the initial 2 weeks.

Cite This Study

Pillai et al. (2026) studied this question.

synapsesocial.com/papers/6984358ff1d9ada3c1fb4748https://doi.org/10.1177/09732179261418412
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Profile of metabolic bone disease in extremely low birth weight (ELBW) and very low birth weight (VLBW) neonates2024 · 2 citations
  2. 2Metabolic bone disease in extremely preterm infants: incidence, risk factors, and outcomes from a structured bone health program2025
  3. 3Clinical profile and predictors of biochemical markers of metabolic bone disease in very preterm neonates: An observational study2025
  4. 4A Cross-Sectional Study on Corrected-Term Screening for Osteopenia/Metabolic Bone Disease of Prematurity in Preterm and Low-Birth-Weight Neonates: Prevalence, Risk Factors, and Feeding-Related Predictors2026
  5. 5Metabolic Bone Disease of Prematurity: A Preventable Morbidity in Very Low Birth Weight Infants2026