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November 20, 2025ACS Applied Materials & Interfaces

Facile Surface Modification of Apatite Nanoparticles for Tailoring Protein Adsorption toward Nano-Bio Interfacial Engineering

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Authors

DNDaichi NodaYKYuhi KinoshitaKKKen'ichiro Kosugi

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Overview

Surface modification demonstrates improved protein adsorption and biocompatibility for hydroxyapatite nanoparticles, indicating enhanced osteoinductivity and reduced blood coagulation.

Key Points

  • Protein adsorption was effectively controlled, enhancing biocompatibility properties of hydroxyapatite nanoparticles.
  • Significant changes in protein interactions were observed, leading to improved functional outcomes for bone applications.
  • Analysis utilized advanced quartz crystal microbalance monitoring, incorporating various protein assays for evaluation.
  • This strategy supports the development of apatite-based implants with tailored biological responses and application potential.

Cite This Study

Noda et al. (2025) studied this question.

synapsesocial.com/papers/6924f074c0ce034ddc34fb78https://doi.org/10.1021/acsami.5c18328
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