Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
November 19, 2025Interventional Cardiology Reviews Research ResourcesOpen Access

Percutaneous Coronary Interventions for Calcified Lesions: A Systematic Review with Meta-analyses of Randomised Trials

View Full Paper
Ask AI
Bookmark
Share

Authors

AKAndreas Torp KristensenPFPascal FaltermeierCKCaroline Barkholt Kamp

Discussion

Loading...

Member takes

Overview

Systematic review examines adverse outcomes in patients with calcified lesions following percutaneous coronary interventions, indicating clinical equipoise in techniques.

Key Points

  • The study aims to evaluate the effects of PCI strategies for calcified lesions on all-cause mortality and serious adverse events.
  • Conducted a systematic review and meta-analysis of randomized trials.
  • Searched CENTRAL, MEDLINE, Embase, and other sources until May 8, 2025.
  • Compared lesion preparation and stenting techniques in patients undergoing PCI for calcified lesions.
  • 31 eligible trials included with 8,453 participants assessed.
  • No effect found on all-cause mortality or serious adverse events from lesion preparation techniques.
  • Meta-analysis rejected the effect of stent polymer coating on all-cause mortality or serious adverse events.

Cite This Study

Kristensen et al. (2025) studied this question.

synapsesocial.com/papers/6924fed1c0ce034ddc350d84https://doi.org/10.15420/icr.2025.10
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Percutaneous Coronary Interventions for Calcified Lesions: A Systematic Review with Meta-analyses of Randomised Trials2025 · 3 citations
  2. 2Percutaneous coronary intervention in calcified stenoses: a protocol for a systematic review with meta-analysis, trial sequential analysis and network meta-analysis2022 · 2 citations
  3. 3Optimization strategies for percutaneous coronary intervention in calcified coronary lesions: current evidence and future directions2026
  4. 4Are Coronary Calcium-Modifying Techniques Levelling the Playfield?2026
  5. 5Comparative Performance of Calcium‐Modification Strategies for Coronary Lesions: A Network Meta‐Analysis of Randomized Trials2026