Key result
New protocol details a planned systematic review of percutaneous treatments for calcified CAD.
Why the study?
Severely calcified coronary stenoses complicate PCI and increase procedural risks, yet these patients are often excluded from trials, leaving little evidence on optimal treatment.
Do various percutaneous treatment options (lesion preparation, stenting, postdilatation) improve all-cause mortality and serious adverse events in patients with calcified coronary artery disease undergoing PCI?
Population
Patients with calcified coronary artery disease undergoing PCI
Comparison
Any percutaneous treatment option including lesion preparation, stenting, or postdilatation techniques
Design
Protocol for a systematic review, meta-analysis, trial sequential analysis, and network meta-analysis
Authors
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Protocol signals evidence gap for calcified CAD PCI; leaves open optimal lesion preparation strategies pending synthesis.
Systematic Review
Do various percutaneous treatment options (lesion preparation, stenting, postdilatation) improve all-cause mortality and serious adverse events in patients with calcified coronary artery disease undergoing PCI?
This protocol outlines a planned systematic review and network meta-analysis to evaluate the efficacy and safety of various percutaneous treatment options for severely calcified coronary stenoses.
Kristensen et al. (2022) conducted a systematic review in calcified coronary artery disease. percutaneous treatment options (lesion preparation, stenting, postdilatation) was evaluated on all-cause mortality and serious adverse events. This protocol outlines a planned systematic review and meta-analysis to evaluate percutaneous treatment options for patients with calcified coronary artery disease.
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