What question did this study set out to answer?

The aim is to review imaging methods that study neuroinflammation and blood-brain barrier dysfunction in various psychiatric and neurological disorders.

November 19, 2025Journal of NeuroinflammationOpen Access

Imaging brain inflammation and blood brain barrier permeability in neurological and psychiatric diseases: a review

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Authors

ZKZanetta Kovbasyuk ETEden Tefera CLChenyang Li

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Implication

This review highlights in vivo imaging methods and their clinical application in understanding neuroinflammation and BBB dysfunction in several disorders.

Key Points

The aim is to review imaging methods that study neuroinflammation and blood-brain barrier dysfunction in various psychiatric and neurological disorders.
Review of imaging methods including TSPO-PET and DCE-MRI
Analysis of clinical applications related to neuroinflammation
Discussion of methodological challenges and variability in studies
Neuroinflammation is a key feature in Alzheimer's, Parkinson's, schizophrenia, and depression.
Imaging techniques provide insights into glial activation and BBB permeability.
Methodological challenges limit the comparability and clinical application of findings.

Cite This Study

Kovbasyuk et al. (2025) studied this question.

synapsesocial.com/papers/6924fed1c0ce034ddc350dd7 https://doi.org/10.1186/s12974-025-03598-x

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Implication

This review highlights in vivo imaging methods and their clinical application in understanding neuroinflammation and BBB dysfunction in several disorders.

Imaging brain inflammation and blood brain barrier permeability in neurological and psychiatric diseases: a review

Discussion

Member takes

Implication

Key Points

Cite This Study

Imaging brain inflammation and blood brain barrier permeability in neurological and psychiatric diseases: a review

Discussion

Member takes

Implication

Key Points

Cite This Study

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