Disinfectant-induced bacterial resistance and antibiotic cross-resistance—mechanisms and clinical relevance

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Review demonstrates the impact of disinfectants on multidrug-resistant bacteria, suggesting the need for improved infection prevention protocols.

Bacterial resistance linked to disinfectant use increases clinical challenges, prolonging hospital stays.
Study finds specific mechanisms like biofilm formation and membrane permeability contribute to resistance.
Assessment of disinfection protocols indicates risks in using disinfectants like quaternary ammonium compounds and chlorhexidine.
Optimizing disinfectant practices may mitigate the rise of multidrug-resistant pathogens in healthcare settings.

Walczak et al. (2025) studied this question.

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Review demonstrates the impact of disinfectants on multidrug-resistant bacteria, suggesting the need for improved infection prevention protocols.