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November 18, 2025Frontiers in EndocrinologyOpen Access

Trabecular bone score in the assessment of bone health in thalassemia major

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Authors

MNMartina Di NotoAXAnastasia XourafaRRRosamaria Rosso

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Overview

Retrospective study assesses bone health and TBS in thalassemia major, suggesting its utility in monitoring osteoporosis and osteopenia.

Key Points

  • This study aims to evaluate bone health in thalassemia major and assess the trabecular bone score as a diagnostic tool.
  • Analyzed 88 adults with thalassemia major for laboratory tests, dual X-ray absorptiometry, and thoracic-lumbar spine X-rays.
  • Utilized trabecular bone score to assess bone quality in relation to bone mass and fracture risk.
  • Observed reduced bone mass density in 96.3% of patients.
  • Trabecular bone score values were markedly reduced but had limited clinical utility in predicting fractures.

Cite This Study

Noto et al. (2025) studied this question.

synapsesocial.com/papers/6924fee6c0ce034ddc3515e1https://doi.org/10.3389/fendo.2025.1635068
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