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November 18, 2025Nature CommunicationsOpen Access

Conservation and variability of long-range interactions in structurally diverse maize genomes

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Authors

HLHan LiuXMXuxu MaSJSiqi Jiang

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Overview

Analysis reveals that hybrid maize shows unique gene regulation patterns, suggesting significant genetic interactions.

Key Points

  • This research investigates the role of long-range chromatin interactions in maize genome variations and hybrid vigor.
  • Assess long-range genomic interactions in two maize inbreds and their reciprocal F1 hybrids
  • Utilize H3K4me3 HiChIP analyses to identify interactions
  • Evaluate inter-allelic interactions and their effects on gene expression patterns.
  • Identified inbred-specific and hybrid-specific chromatin interactions
  • Uncovered dominant and over-dominant expression patterns in hybrid genotypes
  • Noted unexpected gains or losses in interactions in hybrid compared to parent genomes.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/6924fee6c0ce034ddc351636https://doi.org/10.1038/s41467-025-65065-8
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Chromatin accessibility landscape and its association with heterosis in maize hybrids2026 · 1 citations
  2. 2Hybrids reveal accessible chromatin trans genetic associations2025
  3. 3Dynamics of Gene and Allelic Expression During Modern Hybrid Maize Breeding.2026
  4. 4Nonadditive regulation confers phenotypic variation in hybrid maize2025 · 2 citations
  5. 5Genetic architecture of heterosis in maize NCII breeding populations2026