What type of study is this?

This is a Human Clinical Trial study (also classified as: Pre-Registered Trial, RCT).

What question did this study set out to answer?

Evaluate the efficacy of anodal cerebellar transcranial direct current stimulation plus rehabilitation on upper limb recovery post-stroke.

November 18, 2025Frontiers in NeurologyOpen Access

Effects of cerebellar transcranial direct current stimulation on improving post-stroke upper extremity motor function: a protocol for a randomized controlled clinical trial

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Authors

ZHZiqiao Huang JLJiahao LaoWestern University ZCZhibin Chen

Discussion

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Implication

Randomized controlled trial evaluates c-tDCS combined with rehabilitation to improve motor functions in chronic stroke patients, indicating potential benefits of neuromodulation.

Key Points

Evaluate the efficacy of anodal cerebellar transcranial direct current stimulation plus rehabilitation on upper limb recovery post-stroke.
Conduct a double-blind, randomized, sham-controlled trial.
Recruit 48 chronic stroke patients with moderate to severe upper limb motor impairment.
Apply anodal tDCS to the ipsilesional cerebellar hemisphere in the active group, sham in the control.
Administer multimodal assessments including Fugl-Meyer assessment, fNIRS, and TMS-MEPs pre- and post-intervention.
Anticipated improvement in motor functions of the paretic upper extremity with active c-tDCS compared to sham.
Expected increase in cortical excitability as measured by TMS-MEPs in the active treatment group.

Cite This Study

Huang et al. (2025) studied this question.

synapsesocial.com/papers/6924fef4c0ce034ddc351d1e https://doi.org/10.3389/fneur.2025.1670721

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Implication

Randomized controlled trial evaluates c-tDCS combined with rehabilitation to improve motor functions in chronic stroke patients, indicating potential benefits of neuromodulation.

Effects of cerebellar transcranial direct current stimulation on improving post-stroke upper extremity motor function: a protocol for a randomized controlled clinical trial

Discussion

Member takes

Implication

Key Points

Cite This Study

Effects of cerebellar transcranial direct current stimulation on improving post-stroke upper extremity motor function: a protocol for a randomized controlled clinical trial

Discussion

Member takes

Implication

Key Points

Cite This Study

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