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November 18, 2025Scientific ReportsOpen Access

BAGI-assessed green GC-MS method for rapid analysis of paracetamol/metoclopramide in pharmaceuticals and plasma

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Authors

LKLateefa A. Al KhateebMGMohammed GamalMEMohamed A. Elsayed

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Overview

A validated green GC-MS method demonstrates high sensitivity for analyzing paracetamol and metoclopramide in pharmaceuticals and plasma, indicating its utility for quality control.

Key Points

  • The method achieved accurate detection of paracetamol and metoclopramide, confirming its efficacy for pharmaceuticals and plasma.
  • Validation showed strong linearity with r² values of 0.9999 for paracetamol and 0.9988 for metoclopramide, ensuring reliability in results.
  • Utilizing an innovative green approach, the GC-MS method aligns with environmental standards and enhances routine quality control processes.
  • The findings support the integration of fast, green analytical techniques in pharmacokinetic studies, promoting eco-friendly practices.

Cite This Study

Khateeb et al. (2025) studied this question.

synapsesocial.com/papers/6924fef9c0ce034ddc351ee2https://doi.org/10.1038/s41598-025-25388-4
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