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November 1, 2025JACC Case ReportsOpen Access

Successful Transcatheter Mitral Valve Repair for Iatrogenic Chordal Rupture in Cardiac Amyloidosis

Daisuke Kanda Yoshihisa Horizoe Akari Tajima Hiroyuki TABATA Youta Uchiyama Mitsuru Ohishi

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Key Points

To assess the efficacy of transcatheter mitral valve repair in patients with cardiac amyloidosis experiencing iatrogenic chordal rupture.
Evaluated patients with severe iatrogenic mitral regurgitation (MR) due to cardiac amyloidosis
Performed M-TEER as a therapeutic intervention
Monitored outcomes following the procedure
M-TEER showed promising results in reducing mitral regurgitation
Highlighted the potential for improved patient outcomes in this high-risk population

Implication

M-TEER demonstrates life-saving potential in severe mitral regurgitation due to cardiac amyloidosis, indicating a new therapeutic option.

Abstract

M-TEER may be a life-saving therapy for severe iatrogenic MR in patients with advanced cardiac amyloidosis.

Discussion

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Cite This Study

Kanda et al. (2025) studied this question.

synapsesocial.com/papers/692502b787af00ed34ac1f6d https://doi.org/10.1016/j.jaccas.2025.106137

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Successful Transcatheter Mitral Valve Repair for Iatrogenic Chordal Rupture in Cardiac Amyloidosiscase_report · 2025
2Transcatheter mitral edge-to-edge repair in patients with transthyretin cardiac amyloidosis: A four-case seriescase_series · 2026 · 2 citations
3Safety and Feasibility of Transcatheter Edge-to-Edge Repair of Mitral Regurgitation in Cardiac Amyloidosiscohort · 2025 · 3 citations
4Transcatheter Mitral Valve Repair for an Extremely High Surgical Risk Acute Mitral Regurgitation Patientcase_report · 2025
5Transcatheter mitral valve chord repairreview · 2018 · 3 citations

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