What question did this study set out to answer?

To explore the association between physical activity and memory function through brain structural markers.

Association Between Physical Activity and Memory Function: The Role of Brain Structural Markers in a Cross‐Sectional Study

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To explore the association between physical activity and memory function through brain structural markers.
Cross-sectional analysis using data from 19,721 UK Biobank participants aged 45–82
Device-measured physical activity assessed through accelerometers
Memory function evaluated with standardized assessments
Logistic regression used to analyze relationships between variables.
Physical activity associated with improved short-term numeric memory performance
Greater total brain volume, white matter volume, gray matter volume, and hippocampal volume linked to higher physical activity
Smaller white matter hyperintensity volume related to increased physical activity
Pathway analyses indicate brain volumes significantly mediate the relationship between physical activity and memory performance.

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Cross-sectional study reveals physical activity improves memory function in adults, suggesting benefits for brain structure preservation.

Wu et al. (2025) studied this question.

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