Advanced automated methods improve radiosynthesis of [177Lu]Lu-P17-087 and [177Lu]Lu-P17-088, indicating potential for clinical use.
[¹⁷⁷Lu]Lu-P17-087 and [¹⁷⁷Lu]Lu-P17-088 doses can be produced in high yield (95%) and purity (99%) using MiniLu™. Optimized, automated methods using MiniLu™ will facilitate further clinical investigations using [¹⁷⁷Lu]Lu-P17-087 and [¹⁷⁷Lu]Lu-P17-088 by standardizing preparation and reducing radiation exposure to radiochemists.
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Alexoff et al. (2025) studied this question.
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