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November 17, 2025Clinical Research in CardiologyOpen Access

Comparison of iron deficiency markers in patients with advanced heart failure

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Authors

MBMaria BakosovaJKJan KrejciJGJúlius Godava

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Overview

Evaluation reveals iron deficiency correlates with worsened functional capacity in heart failure, highlighting its clinical importance.

Key Points

  • Refine the definition of iron deficiency in advanced heart failure and evaluate its association with clinical characteristics.
  • Included 102 patients with advanced heart failure
  • Monitored iron metabolism parameters beyond conventional tests
  • Compared iron deficiency prevalence using original and updated definitions
  • Measured correlations between individual iron markers and patients’ functional capacity.
  • Prevalence of iron deficiency in advanced heart failure was 65%
  • No significant difference in iron parameters among groups
  • Serum iron correlated strongly with NT-proBNP and CRP
  • Ferritin showed the weakest correlation with functional status.

Cite This Study

Bakosova et al. (2025) studied this question.

synapsesocial.com/papers/692509eec0ce034ddc352a15https://doi.org/10.1007/s00392-025-02775-5
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prevalence of Iron Deficiency in Acute and Chronic Heart Failure According to Different Clinical Definitions2025 · 4 citations
  2. 2Markers of Iron Metabolism and Outcomes in Patients with Heart Failure: A Systematic Review2023 · 22 citations
  3. 3Iron deficiency in worsening heart failure is associated with reduced estimated protein intake, fluid retention, inflammation, and antiplatelet use2019 · 110 citations
  4. 4Iron Deficiency in Heart Failure: Unveiling the Hidden Culprit2024
  5. 5Functional Iron Deficiency in Patients With Heart Failure: A Focus on Its Prevalence Among Hospitalized Patients and Short-Term Outcomes2025