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November 17, 2025Global Spine JournalOpen Access

New-Onset Psychiatric Disorders After Lumbar Fusion: Predictors, Timing, and Risk Stratification

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Authors

ABAlexander M. BallatoriSSShane ShahrestaniATAndy Ton

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Overview

Retrospective cohort study identifies incidence and predictors of psychiatric disorders post-lumbar fusion, indicating screening need.

Key Points

  • To determine the incidence, timing, and predictors of new-onset psychiatric disorders following lumbar fusion surgery.
  • Retrospective cohort study utilizing the Nationwide Readmissions Database (2016-2019).
  • Identified adults undergoing elective inpatient lumbar fusion, excluding those with preexisting psychiatric diagnoses.
  • Evaluated new-onset depression, anxiety, suicidal ideation, and homicidal ideation within 12 months post-surgery.
  • Among 839,576 patients, 12,011 developed depression, 11,828 anxiety, 916 suicidal ideation, and 63 homicidal ideation.
  • Most psychiatric diagnoses occurred within 90 days postoperatively with peak incidence around 3 weeks.
  • Opioid use increased odds of suicidal ideation (OR 2.13) and anxiety (OR 1.26), while Medicaid insurance was the strongest predictor of suicidal (OR 3.69) and homicidal ideation (OR 6.41).

Cite This Study

Ballatori et al. (2025) studied this question.

synapsesocial.com/papers/692509f6c0ce034ddc352d0bhttps://doi.org/10.1177/21925682251400284
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