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April 26, 2026Global Spine JournalOpen Access

The Impact of Major Depressive Disorder on Somatic and Psychiatric Outcomes Following Elective Single-Level Lumbar Fusion: A Propensity Score-Matched Analysis

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Authors

STSri TummalaHCHetsinhji ChavdaTSTarun Sontam

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Overview

Retrospective analysis shows preoperative MDD increases psychiatric and somatic issues post-surgery, suggesting screening is beneficial.

Key Points

  • This study aims to assess the impact of major depressive disorder on the risk of adverse psychiatric and somatic outcomes following elective single-level lumbar fusion.
  • Retrospective database study utilizing a national electronic health record network.
  • Patients with recurrent MDD were compared with those without MDD using one-to-one propensity score matching.
  • Outcomes were assessed at 90 days and 1 year after surgery.
  • Patients with MDD had higher rates of newly diagnosed psychiatric conditions at both follow-up points.
  • MDD was associated with increased postoperative somatic symptom diagnoses, such as chest pain and dizziness.
  • Higher emergency department utilization and increased inpatient readmission rates were observed at 1 year, with no differences in reoperation rates or mortality.

Cite This Study

Tummala et al. (2026) studied this question.

synapsesocial.com/papers/69edacbd4a46254e215b4793https://doi.org/10.1177/21925682261445029
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