What question did this study set out to answer?

To describe the clinical presentation and diagnostic techniques in pediatric acute promyelocytic leukemia (APL).

Pediatric acute promyelocytic leukemia: Insights from a tertiary care center

View Full Paper

Ask AI

Bookmark

Authors

Case series reports increased leucocytosis in pediatric acute promyelocytic leukemia, indicating urgent need for timely diagnosis and management.

To describe the clinical presentation and diagnostic techniques in pediatric acute promyelocytic leukemia (APL).
Case series of four children diagnosed with APL over one year.
Diagnosis confirmation using cytogenetics to detect PML::RARA gene.
Analysis of peripheral blood, cellular morphology, and flow cytometry data.
All cases showed leucocytosis and had varying expression of key markers.
Two patients were identified with hypergranular variants, the other two with microgranular variants.
Flow cytometry results indicated positive expression of CD117 and cytoplasmic myeloperoxidase, with specific markers associated with prognosis.

Singh et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark

Case series reports increased leucocytosis in pediatric acute promyelocytic leukemia, indicating urgent need for timely diagnosis and management.