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November 17, 2025Med ResearchOpen Access

The Global Burden of Leukemia, 1990–2021: A Systematic Analysis of Prevalence, DALYs, and Risk Factors From the Global Burden of Disease Study

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Authors

YWYu-Ping WuHZHaini ZhangSLShuang Luo

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Overview

Systematic analysis reveals increased leukemia prevalence and significant risk factors, emphasizing regional disparities in health outcomes.

Key Points

  • This analysis assesses the global burden of leukemia, examining prevalence and disability-adjusted life years (DALYs) from 1990 to 2021.
  • Systematic assessment using data from the Global Burden of Disease Study.
  • Analysis of leukemia prevalence and DALYs across 204 countries and territories.
  • Risk attribution analyses for modifiable factors such as body mass index and tobacco use.
  • 28.0% increase in leukemia cases overall and a 16.2% decline in DALYs from 1990 to 2021.
  • Men exhibited higher DALY rates than women, with varying patterns by age and geographic regions.
  • Chronic lymphocytic leukemia was the most prevalent subtype; acute myeloid leukemia accounted for the largest proportion of DALYs.

Cite This Study

Wu et al. (2025) studied this question.

synapsesocial.com/papers/692509f6c0ce034ddc352defhttps://doi.org/10.1002/mdr2.70036
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