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December 8, 2025BloodOpen Access

Global, regional, and national trends in the burden of chronic myeloid leukemia from 1990 to 2021: A comprehensive analysis of the 2021 global burden of disease study and projections to 2050

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Authors

QHQinglin HuHJHongmei Jing

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Overview

Analysis reveals increasing prevalence and mortality rates of chronic myeloid leukemia, indicating urgent public health needs.

Key Points

  • This study assesses global trends in the burden of chronic myeloid leukemia from 1990 to 2021 and projects future metrics.
  • Utilized data from the Global Burden of Disease study
  • Analyzed metrics including incidence, prevalence, mortality, and disability-adjusted life years
  • Applied advanced statistical methodologies such as decomposition analysis and ARIMA modeling
  • In 2021, age-standardized rates for incidence were 0.43 per 100,000 population
  • Males showed higher incidence and mortality rates across age groups
  • Health inequality was observed, with higher outcomes in high-SDI regions
  • Population growth is projected to increase disease burden, with minor changes in other metrics by 2050

Cite This Study

Hu et al. (2025) studied this question.

synapsesocial.com/papers/69362f6c4fa91c937236df89https://doi.org/10.1182/blood-2025-6210
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Also Consider

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