A Mixing System for Uniform, Reproducible Viscous Bioinks Preparation

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The SMX-style mixer achieved uniform mixing and low simulated shear stress during bioink preparation.
Viability of A549, NIH-3T3, and human lung fibroblasts remained above 96% after using the SMX-style mixer for mixing.
Analysis used rheology and shear-thinning measurements to assess the effectiveness of static mixers.
This approach enables consistent fabrication of cell-laden bioinks for extrusion 3D bioprinting with high viability rates.

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Evaluation of static mixers improved shear stress and cell viability in bioinks, indicating enhanced tissue construct quality in 3D bioprinting.

Singer et al. (2025) studied this question.

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Evaluation of static mixers improved shear stress and cell viability in bioinks, indicating enhanced tissue construct quality in 3D bioprinting.