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November 13, 2025American Journal of NeuroradiologyOpen Access

Prolonged Venous Transit on Perfusion Imaging: An Evolving Marker of Outcomes in Large Vessel Occlusion Stroke – A Comprehensive Review

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Authors

JKJay KakadiyaDLDhairya A LakhaniHSHamza A SalimJohns Hopkins Hospital

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Overview

Comprehensive review demonstrates prolonged venous transit impacts outcomes in acute ischemic stroke, implying its role in evaluating prognosis and therapy effectiveness.

Key Points

  • This review evaluates prolonged venous transit on perfusion imaging as a predictive marker for outcomes in acute ischemic stroke.
  • Comprehensive review of existing literature on prolonged venous transit and its impact on stroke outcomes.
  • Assessment of arterial and venous metrics post mechanical thrombectomy and their correlations with patient prognosis.
  • Analysis of studies examining prolonged venous transit as a marker for microvascular dysfunction and outcomes.
  • Prolonged venous transit associated with worse NIHSS scores and larger infarct volumes.
  • Demonstrated strong interobserver agreement on prolonged venous transit measurements.
  • PVT provides superior prognostic performance compared to traditional arterial metrics.

Cite This Study

Kakadiya et al. (2025) studied this question.

synapsesocial.com/papers/692523bbc0ce034ddc354954https://doi.org/10.3174/ajnr.a9100
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prolonged venous transit on perfusion imaging is associated with higher odds of mortality in successfully reperfused patients with large vessel occlusion stroke2024 · 38 citations
  2. 2Gradation of Prolonged Venous Transit on Perfusion Imaging Highlights the Association of Deep Venous Drainage Impairment with Unfavorable Functional Outcome in Successfully Reperfused Anterior Circulation Large-Vessel-Occlusion Stroke2026
  3. 3Prolonged Venous Transit Is Associated With Lower Likelihood of Favorable Clinical Recovery in Reperfused Anterior Circulation Large‐Vessel Occlusion Stroke2024 · 11 citations
  4. 4Abstract TP250: Prolonged Venous Transit is Associated with Unfavorable Functional Outcomes in Anterior Circulation Distal Medium Vessel Occlusion Strokes2026
  5. 5Abstract DP022: Gradation of Prolonged Venous Transit Highlights the Impact of Deep Venous Drainage Impairment in Successfully Reperfused Anterior Circulation Large Vessel Occlusion Stroke2026