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November 12, 2025Frontiers in MedicineOpen Access

Is it necessary to perform a diagnostic hysteroscopy before the first embryo transfer?—A retrospective study

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Authors

JFJian-ye FangJFJian-ye FangJFJian-ye Fang

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Overview

Retrospective study finds diagnostic hysteroscopy improves clinical pregnancy rates in women undergoing embryo transfer, indicating potential benefits for reproductive outcomes.

Key Points

  • This research assesses if diagnostic hysteroscopy before embryo transfer enhances IVF outcomes.
  • Conducted a retrospective descriptive study from October 2019 to March 2023 at a hospital in China.
  • Included women under 45 with normal uterine cavities undergoing their first fresh embryo transfer via IVF or ICSI.
  • Compared reproductive outcomes between hysteroscopy and non-hysteroscopy groups.
  • 49.63% of hysteroscopy patients had abnormal uterine findings, mainly endometrial polyps (30.03%).
  • The hysteroscopy group had a significantly lower rate of good-quality embryos compared to the non-hysteroscopy group (50.38% vs. 75.11%, p < 0.05).
  • After adjustments, clinical pregnancy rates were significantly higher in the hysteroscopy group (OR: 1.51, p = 0.004).

Cite This Study

Fang et al. (2025) studied this question.

synapsesocial.com/papers/692523d9c0ce034ddc3557f4https://doi.org/10.3389/fmed.2025.1690944
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impact of hysteroscopy on pregnancy outcomes in women with endometriosis-associated infertility undergoing their first frozen-thawed embryo transfer: a retrospective cohort study2026
  2. 2The Value of Routine Hysteroscopy Before First Embryo Transfer in Infertile Women With a History of Ectopic Pregnancy: A Propensity Score-Matched Analysis2025
  3. 3The effect of hysteroscopy prior to intrauterine insemination with donor spermatozoon on pregnancy outcomes: a retrospective cohort study2026
  4. 4Hysteroscopy: The Uterine Stethoscope Decoding Implantation Failures2025
  5. 5Is it necessary to perform a routine hysteroscopy before first embryo transfer in patients with previous ectopic pregnancy history: A propensity score matching analysis?2024