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November 12, 2025Transplant InternationalOpen Access

Infection Risk in Older Kidney Transplant Recipients: An Analysis in the Era of Expanded Age Limits

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Authors

MFMarina FayosMFMarina FayosLCLaura Corbella

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Overview

Cohort study reveals increased infection risk in older kidney transplant recipients, indicating age impacts incidence significantly.

Key Points

  • The aim is to analyze infection risk in kidney transplant recipients, especially concerning their age.
  • Prospective single-center cohort study of 712 kidney transplant patients from 2014 to 2022.
  • Recipient ages were analyzed in 10-year strata and categorized by age thresholds.
  • Used univariable and multivariable regression models to assess infection incidence.
  • Each 10-year increase in age correlates with a higher overall infection risk (SHR: 1.18).
  • Bacterial infection shows a similar increase (SHR: 1.17); opportunistic infection increases more significantly (SHR: 1.26).
  • Older recipients (≥60) have a higher overall infection risk (aSHR: 1.25), while those ≥70 have a higher risk of opportunistic infection (aSHR: 1.54).

Cite This Study

Fayos et al. (2025) studied this question.

synapsesocial.com/papers/69252e83c0ce034ddc355a59https://doi.org/10.3389/ti.2025.15594
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