What question did this study set out to answer?

To investigate the molecular and metabolic responses of Gymnocypris eckloni to thermal stress using multi-omics approaches.

November 12, 2025AnimalsOpen Access

Physiological Responses to Thermal Stress in the Liver of Gymnocypris eckloni Revealed by Multi-Omics

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Authors

MNMiaomiao Nie WNWeilin Ni ZWZhenji Wang

Discussion

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Overview

Analysis reveals dysregulation in glucose and fatty acid metabolism in Gymnocypris eckloni under thermal stress, highlighting critical pathways for adaptation.

Key Points

To investigate the molecular and metabolic responses of Gymnocypris eckloni to thermal stress using multi-omics approaches.
Integrated RNA-seq, miRNA-seq, and LC-MS-based metabolomic analyses
Comparative analysis of liver tissue from fish exposed to chronic thermal stress versus control conditions
Histopathological examination to assess structural damage
Significant dysregulation of genes involved in energy metabolism under thermal stress
Alterations observed in amino acid, fatty acid, and glucose metabolism
Histopathological examination indicated structural damage in liver tissue exposed to heat stress

Cite This Study

Nie et al. (2025) studied this question.

synapsesocial.com/papers/69252e8bc0ce034ddc355da3 https://doi.org/10.3390/ani15223272

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November 12, 2025AnimalsOpen Access

Physiological Responses to Thermal Stress in the Liver of Gymnocypris eckloni Revealed by Multi-Omics

View Full Paper

Ask AI

Bookmark

Authors

MNMiaomiao Nie WNWeilin Ni ZWZhenji Wang

Discussion

Member takes

Overview

Analysis reveals dysregulation in glucose and fatty acid metabolism in Gymnocypris eckloni under thermal stress, highlighting critical pathways for adaptation.

Key Points

To investigate the molecular and metabolic responses of Gymnocypris eckloni to thermal stress using multi-omics approaches.
Integrated RNA-seq, miRNA-seq, and LC-MS-based metabolomic analyses
Comparative analysis of liver tissue from fish exposed to chronic thermal stress versus control conditions
Histopathological examination to assess structural damage
Significant dysregulation of genes involved in energy metabolism under thermal stress
Alterations observed in amino acid, fatty acid, and glucose metabolism
Histopathological examination indicated structural damage in liver tissue exposed to heat stress

Cite This Study

Nie et al. (2025) studied this question.

synapsesocial.com/papers/69252e8bc0ce034ddc355da3 https://doi.org/10.3390/ani15223272

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