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November 11, 2025GenesOpen Access

Analysis of Human Degraded DNA in Forensic Genetics

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Authors

IZIrena Zupanič-Pajnič

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Overview

This review reveals factors influencing DNA preservation in forensics, suggesting next-generation sequencing enhances genetic profiling.

Key Points

  • To examine how environmental conditions impact DNA preservation and degradation in forensic contexts.
  • Review of literature on DNA degradation factors
  • Analysis of the efficacy of various DNA typing methods
  • Discussion of advancements in next-generation sequencing technologies
  • Evaluation of short tandem repeat and SNP profiling methods
  • Environmental factors like temperature and humidity significantly affect DNA preservation
  • Next-generation sequencing improves genetic profiling of degraded DNA
  • Short amplicon lengths are crucial for successful amplification from fragmented DNA
  • Genetic markers such as SNPs offer better identification options in challenging cases.

Cite This Study

Irena Zupanič-Pajnič (2025) studied this question.

synapsesocial.com/papers/69252e90c0ce034ddc35611bhttps://doi.org/10.3390/genes16111375
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