What does this research mean for the field?

Successful DNA-based identification of burned and degraded human remains requires a triage-based framework that integrates optimized tissue sampling, particularly of teeth and dense cortical bone, with hierarchical genetic analyses including mtDNA, Y-STRs, SNPs, and massively parallel sequencing. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This review assesses effective DNA-based methods for identifying degraded human remains in forensic contexts.

July 30, 2026GenesOpen Access

Genetic Identification of Burned Human Remains: A Systematic Review

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Authors

FSFrancesco SessaPegaso University MFMartina FrancavigliaUniversity of Catania EDEmina DerviševićUniversity of Sarajevo

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Overview

Systematic review evaluates DNA identification methods for degraded remains, proposing optimized workflows for forensic use.

Key Points

This review assesses effective DNA-based methods for identifying degraded human remains in forensic contexts.
Conducted a systematic literature search in Scopus and Web of Science until June 2026.
Included 37 studies focusing on DNA analysis of degraded, thermally altered, or compromised remains.
Organized data into thematic categories: core DNA analysis, advanced molecular technologies, and DVI applications.
DNA recovery is influenced by thermal exposure, tissue type, and sampling strategy.
Identification rates exceed 90–95% when using multidisciplinary workflows for DVI cases.
Autosomal STR profiling combined with mtDNA and Y-STRs enhances success in degraded samples.

Cite This Study

Sessa et al. (2026) studied this question.

synapsesocial.com/papers/6a6af51160e2b924d3ea0bc7 https://doi.org/10.3390/genes17080881

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July 30, 2026GenesOpen Access

Genetic Identification of Burned Human Remains: A Systematic Review

View Full Paper

Ask AI

Bookmark

Authors

FSFrancesco SessaPegaso University MFMartina FrancavigliaUniversity of Catania EDEmina DerviševićUniversity of Sarajevo

Discussion

Member takes

Overview

Systematic review evaluates DNA identification methods for degraded remains, proposing optimized workflows for forensic use.

Key Points

This review assesses effective DNA-based methods for identifying degraded human remains in forensic contexts.
Conducted a systematic literature search in Scopus and Web of Science until June 2026.
Included 37 studies focusing on DNA analysis of degraded, thermally altered, or compromised remains.
Organized data into thematic categories: core DNA analysis, advanced molecular technologies, and DVI applications.
DNA recovery is influenced by thermal exposure, tissue type, and sampling strategy.
Identification rates exceed 90–95% when using multidisciplinary workflows for DVI cases.
Autosomal STR profiling combined with mtDNA and Y-STRs enhances success in degraded samples.

Cite This Study

Sessa et al. (2026) studied this question.

synapsesocial.com/papers/6a6af51160e2b924d3ea0bc7 https://doi.org/10.3390/genes17080881

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