PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
Synapse
⌘+K
Synapse
November 10, 2025Frontiers in NeurologyOpen Access

Accuracy of computed tomography perfusion-defined ischemic core and follow-up infarction after basilar artery thrombectomy

View Full Paper
Ask AI
Bookmark
Share

Authors

PCPengjun ChenXLXia LiYHYechao Huang

Discussion

Loading...

Member takes

Overview

Retrospective analysis shows cerebral blood flow threshold aids ischemic core detection in basilar artery occlusion, indicating improved treatment decisions.

Key Points

  • Define optimal threshold for ischemic core using computed tomography perfusion in basilar artery occlusion patients.
  • Retrospective analysis of 91 patients with basilar artery occlusion
  • Thresholds assessed: cerebral blood flow < 10 mL/100 g/min
  • Used Syngo.via for analysis and RAPID for time to maximum
  • Extent of infarction assessed using Alberta Stroke Program Early CT Score
  • Statistical analysis included ICC and receiver operating characteristic analyses.
  • CBF < 10 mL/100 g/min showed good agreement with follow-up infarction (ICC: 0.81)
  • Best performance for detecting midbrain and pontine infarction, AUC 0.90
  • Nine cases of overestimation or underestimation observed.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/69253a16c0ce034ddc356c99https://doi.org/10.3389/fneur.2025.1678450
View Full Paper
Ask AI
Bookmark
Share