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November 7, 2025NutrientsOpen Access

Effects of Moringa oleifera Lam. Supplementation on Cardiometabolic Outcomes: A Meta-Analysis of Randomized Controlled Trials with GRADE Assessment

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Authors

DCDiana CrișanLGLaura GavrilașRPRamona Păltinean

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Overview

Meta-analysis shows limited cardiometabolic benefits of moringa supplementation in adults, suggesting need for more RCTs.

Key Points

  • To synthesize evidence on the impact of Moringa oleifera supplementation on cardiometabolic outcomes based on RCTs.
  • Conducted systematic search of PubMed, Scopus, and Web of Science until April 2025.
  • Analyzed eligible RCTs with a minimum duration of two weeks and reported cardiometabolic outcomes.
  • Performed random-effects meta-analyses and assessed risk of bias with Cochrane RoB 2 tool.
  • Nine RCTs involving 341 participants in intervention and 308 in control met inclusion criteria.
  • Moringa supplementation showed no significant effects on most outcomes, with a modest reduction in diastolic blood pressure.
  • Observed heterogeneity and methodological limitations reduced the certainty of evidence.

Cite This Study

Crișan et al. (2025) studied this question.

synapsesocial.com/papers/69253a39c0ce034ddc357cfchttps://doi.org/10.3390/nu17223501
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Effect of <scp> <i>Moringa oleifera</i> </scp> on Body Weight and Blood Pressure: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials2026
  2. 2Effect of &lt;em&gt;Moringa oleifera &lt;/em&gt;Leaf Supplementation on Glycemic and Hemodynamic Parameters in Type 2 Diabetes Mellitus: A Randomised Controlled Trial2025
  3. 3Can Moringa oleifera improve sports performance? A systematic literature review2025
  4. 4Facility-based prospective cohort study to evaluate Moringa stenopetala based diet consumption in management of diabetes and hypertension in South Ethiopia2026 · 1 citations
  5. 5Therapeutic potential of Moringa oleifera Lam. in metabolic disorders: A molecular overview2025